Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol

K. Ray, Kausik; Bays, Harold; L. Catapano, Alberico; D. Lalwani, Narendra; T. Bloedon, LeAnne; Ren Sterling, Lulu; Robinson, Paula; M. Ballantyne, Christie

doi:10.1056/nejmoa1803917

Public

Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol

Published in New England Journal of Medicine • Mar 13, 2019

Authors:

Kausik K. Ray

Harold Bays

Alberico L. Catapano

Abstract

BACKGROUND: Short-term studies have shown that bempedoic acid, an inhibitor of ATP citrate lyase, reduces levels of low-density lipoprotein (LDL) cholesterol. Data are limited regarding the safety and efficacy of bempedoic acid treatment in long-term studies involving patients with hypercholesterole...

Subject

Medicine

Adverse effect

Placebo

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