Serum Levels of MicroRNA-371a-3p (M371 Test) as a New Biomarker of Testicular Germ Cell Tumors: Results of a Prospective Multicentric Study

Dieckmann, Klaus‐Peter; Radtke, Arlo; Géczi, Lajos; Matthies, Cord; Anheuser, Petra; Eckardt, Ulrike; Sommer, Jörg; Zengerling, Friedemann; Trenti, Emanuela; Pichler, Renate; Belz, Hanjo; Zastrow, Stefan; Winter, Alexander; Melchior, Sebastian; Hammel, Johannes; Kranz, Jennifer; Bolten, Marius; Krege, S.; Haben, Björn; Loidl, Wolfgang; Ruf, Christian; Heinzelbecker, Julia; Heidenreich, Axel; Frederik Cremers, Jann; Oing, Christoph; Hermanns, Thomas; D. Fankhauser, Christian; Gillessen, Silke; Reichegger, Hermann; Cathomas, Richard; Pichler, Martin; Hentrich, Marcus; Eredics, Klaus; Lorch, Anja; Wülfing, Christian; Peine, Sven; Wosniok, Werner; Bokemeyer, Carsten; Belge, Gazanfer

doi:10.1200/jco.18.01480

Public

Serum Levels of MicroRNA-371a-3p (M371 Test) as a New Biomarker of Testicular Germ Cell Tumors: Results of a Prospective Multicentric Study

Published in Journal of Clinical Oncology • Mar 15, 2019

Authors:

Klaus‐Peter Dieckmann

Arlo Radtke

Lajos Géczi

Abstract

PURPOSE: Previous studies suggested that serum levels of microRNA (miR)-371a-3p (so-called M371 test) have a much higher sensitivity and specificity than the classic markers of testicular germ cell tumors (GCTs) and are applicable toward both seminoma and nonseminoma. We sought to confirm the useful...

Subject

Seminoma

Human chorionic gonadotropin

Medicine

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