Curcumin-primed exosomes potently ameliorate cognitive function in AD mice by inhibiting hyperphosphorylation of the Tau protein through the AKT/GSK-3β pathway

Wang, Hao; Sui, Haijuan; Zheng, Yan; Jiang, Yibin; Shi, Yijie; Liang, Jia; Zhao, Liang

doi:10.1039/c9nr01255a

Public

Curcumin-primed exosomes potently ameliorate cognitive function in AD mice by inhibiting hyperphosphorylation of the Tau protein through the AKT/GSK-3β pathway

Published in Nanoscale • Jan 1, 2019

Authors:

Hao Wang

Haijuan Sui

Yan Zheng

Abstract

Alzheimer's disease (AD) is the progressive development of fatal neurodegenerative diseases. Owing to the unclearness of the pathogenesis of AD and the failure of the drug to cross the blood-brain barrier (BBB), there is currently a lack of effective diagnostic and therapeutic approaches in the trea...

Subject

Curcumin

Hyperphosphorylation

Microvesicles

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