Exosomes from M1-Polarized Macrophages Enhance Paclitaxel Antitumor Activity by Activating Macrophages-Mediated Inflammation

Wang, Piaopiao; Wang, Huihui; Huang, Qianqian; Peng, Can; Yao, Liang; Chen, Hong; Qiu, Zhen; Wu, Yifan; Wang, Lei; Chen, Weidong

doi:10.7150/thno.30716

Public

Exosomes from M1-Polarized Macrophages Enhance Paclitaxel Antitumor Activity by Activating Macrophages-Mediated Inflammation

Published in Theranostics • Jan 1, 2019

Authors:

Piaopiao Wang

Huihui Wang

Qianqian Huang

Abstract

Objective: Exosomes (Exos) are membrane-encased vesicles derived by nearly all cell types for intercellular communication and regulation. They also received attention for their use as natural therapeutic platforms and drug delivery system. Classically activated M1 macrophages suppress tumor growth b...

Subject

Microvesicles

Paclitaxel

Inflammation

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