Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality

Marklund, Matti; H.Y. Wu, Jason; Imamura, Fumiaki; C. Del Gobbo, Liana; Fretts, Amanda; de Goede, Janette; Shi, Peilin; Tintle, Nathan; Wennberg, Maria; Aslibekyan, Stella; Chen, Tzu-An; C. de Oliveira Otto, Marcia; Hirakawa, Yoichiro; Højmark Eriksen, Helle; Kröger, Janine; Laguzzi, Federica; Lankinen, Maria; A. Murphy, Rachel; Prem, Kiesha; Samieri, Cécilia; Virtanen, Jyrki; C. Wood, Alexis; Wong, Kerry; Yang, Wei-Sin; Zhou, Xia; Baylin, Ana; M.A. Boer, Jolanda; A. Brouwer, Ingeborg; Campos, Hannia; H. M. Chaves, Paulo; Chien, Kuo-Liong; de Faire, Ulf; Djoussé, Luc; Eiriksdottir, Gudny; El-Abbadi, Naglaa; G. Forouhi, Nita; Michael Gaziano, J.; M. Geleijnse, Johanna; Gigante, Bruna; Giles, Graham; Guallar, Eliseo; Gudnason, Vilmundur; Harris, Tamara; S. Harris, William; Helmer, Catherine; Hellenius, Mai-Lis; Hodge, Allison; B. Hu, Frank; F. Jacques, Paul; Jansson, Jan-Håkan; Kalsbeek, Anya; Khaw, Kay-Tee; Koh, Woon-Puay; Laakso, Markku; Leander, Karin; Lin, Hung-Ju; Lind, Lars; Luben, Robert; Luo, Juhua; McKnight, Barbara; Mursu, Jaakko; Ninomiya, Toshiharu; Overvad, Kim; M. Psaty, Bruce; Rimm, Eric; B. Schulze, Matthias; Siscovick, David; Skjelbo Nielsen, Michael; V. Smith, Albert; T. Steffen, Brian; Steffen, Lyn; Sun, Qi; Sundström, Johan; Y. Tsai, Michael; Tunstall-Pedoe, Hugh; I. J. Uusitupa, Matti; M. van Dam, Rob; Veenstra, Jenna; Monique Verschuren, W.M.; Wareham, Nick; Willett, Walter; Woodward, Mark; Yuan, Jian-Min; Micha, Renata; N. Lemaitre, Rozenn; Mozaffarian, Dariush; Risérus, Ulf; the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE), For

doi:10.1161/circulationaha.118.038908

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Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality

Shared by NobleBlocks on May 21, 2019 • 12:00 AM UTC

Authors:

Matti Marklund

Jason H.Y. Wu

Fumiaki Imamura

Abstract

Background: Global dietary recommendations for and cardiovascular effects of linoleic acid, the major dietary omega-6 fatty acid, and its major metabolite, arachidonic acid, remain controversial. To address this uncertainty and inform international recommendations, we evaluated how in vivo circulati...

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