Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.

Dan-Qian, Chen,; Gang, Cao,; Hua, Chen,; Christos P, Argyopoulos,; Hui, Yu,; Wei, Su,; Lin, Chen,; David C, Samuels,; Shougang, Zhuang,; George P, Bayliss,; Shilin, Zhao,; Xiao-Yong, Yu,; Nosratola D, Vaziri,; Ming, Wang,; Dan, Liu,; Jia-Rong, Mao,; Shi-Xing, Ma,; Jin, Zhao,; Yuan, Zhang,; You-Quan, Shang,; Huining, Kang,; Fei, Ye,; Xiao-Hong, Cheng,; Xiang-Ri, Li,; Li, Zhang,; Mei-Xia, Meng,; Yan, Guo,; Ying-Yong, Zhao,

doi:10.1038/s41467-019-09329-0

Public

Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.

Published in Nature communications • Apr 1, 2019

Authors:

Chen, Dan-Qian

Cao, Gang

Chen, Hua

Abstract

Early detection and accurate monitoring of chronic kidney disease (CKD) could improve care and retard progression to end-stage renal disease. Here, using untargeted metabolomics in 2155 participants including patients with stage 1-5 CKD and healthy controls, we identify five metabolites, including 5...

Subject

Acetylcarnitine

Animals

Canavanine

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!