Exosome secreted from adipose-derived stem cells attenuates diabetic nephropathy by promoting autophagy flux and inhibiting apoptosis in podocyte

Jin, Juan; Shi, Yifen; Gong, Jianguang; Zhao, Li; Li, Yiwen; He, Qiang; Huang, He

doi:10.1186/s13287-019-1177-1

Public

Exosome secreted from adipose-derived stem cells attenuates diabetic nephropathy by promoting autophagy flux and inhibiting apoptosis in podocyte

Published in Stem Cell Research & Therapy • Mar 15, 2019

Authors:

Juan Jin

Yifen Shi

Jianguang Gong

Abstract

BACKGROUND: It is confirmed that adipose-derived stem cells (ADSCs) transplantation effectively relieves kidney fibrosis and type 2 diabetes disease in mice. Currently, exosome from urine-derived stem cells (USCs) can protect type 1 diabetes-mediated kidney injury and attenuate podocyte damage in di...

Subject

Podocyte

Exosome

Cell biology

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