Fusobacterium nucleatum Contributes to the Carcinogenesis of Colorectal Cancer by Inducing Inflammation and Suppressing Host Immunity

Wu, Jiao; Li, Qing; Fu, Xiangsheng

doi:10.1016/j.tranon.2019.03.003

Public

Fusobacterium nucleatum Contributes to the Carcinogenesis of Colorectal Cancer by Inducing Inflammation and Suppressing Host Immunity

Published in Translational Oncology • Apr 12, 2019

Authors:

Jiao Wu

Qing Li

Xiangsheng Fu

Abstract

The presence of Fusobacterium nucleatum (F. nucleatum) in the gut is associated with the development of colorectal cancer (CRC). F. nucleatum promotes tumor development by inducing inflammation and host immune response in the CRC microenvironment. Adhesion to the intestinal epithelium by the cell su...

Subject

Fusobacterium nucleatum

Immune system

Inflammation

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