Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration

Leung, Samuel; O. Nielsen, Torsten; Zabaglo, Lila; Arun, Indu; Badve, Sunil; Bane, Anita; M.S. Bartlett, John; Borgquist, Signe; C. Chang, Martin; Dodson, Andrew; Ehinger, Anna; Fineberg, Susan; M. Focke, Cornelia; Gao, Dongxia; M. Gown, Allen; Gutiérrez, Carolina; Hugh, Judith; Kos, Zuzana; Lænkholm, Anne‐Vibeke; G. Mastropasqua, Mauro; Moriya, Takuya; Nofech‐Mozes, Sharon; Kent Osborne, C.; Penault‐Llorca, Frédérique; Piper, Tammy; Sakatani, Takashi; Salgado, Roberto; Starczynski, Jane; Sugie, Tomoharu; van der Vegt, Bert; Viale, Giuseppe; F. Hayes, Daniel; M. McShane, Lisa; Dowsett, Mitch; behalf of the International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group (BIG‐NABCG), on

doi:10.1111/his.13880

Public

Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration

Published in Histopathology • Apr 24, 2019

Authors:

Samuel Leung

Torsten O. Nielsen

Lila Zabaglo

Abstract

AIMS: The nuclear proliferation marker Ki67 assayed by immunohistochemistry has multiple potential uses in breast cancer, but an unacceptable level of interlaboratory variability has hampered its clinical utility. The International Ki67 in Breast Cancer Working Group has undertaken a systematic prog...

Subject

Breast cancer

Medicine

Immunohistochemistry

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