A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling

Zheng, Xiao; Chen, Lujun; Zhou, You; Wang, Qi; Zheng, Zhuojun; Xu, Bin; Wu, Chen; Zhou, Qi; Hu, Wenwei; Wu, Changping; Jiang, Jingting

doi:10.1186/s12943-019-1010-6

Public

A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling

Published in Molecular Cancer • Mar 29, 2019

Authors:

Xiao Zheng

Lujun Chen

You Zhou

Abstract

BACKGROUND: It has been well established that circular RNAs (circRNAs) play an important regulatory role during tumor progression. Recent studies have indicated that even though circRNAs generally regulate gene expression through miRNA sponges, they may encode small peptides in tumor pathogenesis. H...

Subject

Biology

Carcinogenesis

Circular RNA

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