Regulation of Mitochondrial Biogenesis as a Way for Active Longevity: Interaction Between the Nrf2 and PGC-1α Signaling Pathways

P. Gureev, Artem; A. Shaforostova, Ekaterina; Н. Попов, В.

doi:10.3389/fgene.2019.00435

Public

Regulation of Mitochondrial Biogenesis as a Way for Active Longevity: Interaction Between the Nrf2 and PGC-1α Signaling Pathways

Published in Frontiers in Genetics • May 14, 2019

Authors:

Artem P. Gureev

Ekaterina A. Shaforostova

В. Н. Попов

Abstract

Aging is a general degenerative process related to deterioration of cell functions in the entire organism. Mitochondria, which play a key role in energy homeostasis and metabolism of reactive oxygen species (ROS), require the lifetime control and constant renewal. This explains recently peaked inter...

Subject

Mitochondrial biogenesis

Mitochondrion

Regulator

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