circRNA_0025202 Regulates Tamoxifen Sensitivity and Tumor Progression via Regulating the miR-182-5p/FOXO3a Axis in Breast Cancer

Sang, Yuting; Chen, Bing; Song, Xiaojin; Li, Yaming; Liang, Yiran; Han, Dianwen; Zhang, Ning; Zhang, Hanwen; Liu, Ying; Chen, Tong; Li, Chen; Wang, Lijuan; Zhao, Wenjing; Yang, Qifeng

doi:10.1016/j.ymthe.2019.05.011

Public

circRNA_0025202 Regulates Tamoxifen Sensitivity and Tumor Progression via Regulating the miR-182-5p/FOXO3a Axis in Breast Cancer

Published in Molecular Therapy • May 17, 2019

Authors:

Yuting Sang

Bing Chen

Xiaojin Song

Abstract

Tamoxifen is the most commonly used endocrine therapy for patients with hormone receptor (HR)-positive breast cancer. Despite its initial therapeutic efficacy, many patients eventually develop drug resistance, which remains a serious clinical challenge. To investigate roles of circular RNAs (circRNA...

Subject

Tamoxifen

Breast cancer

Cancer research

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