Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer’s Disease

Hansson, Oskar; Lehmann, Sylvain; Otto, Markus; Zetterberg, Henrik; Lewczuk, Piotr

doi:10.1186/s13195-019-0485-0

Public

Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer’s Disease

Published in Alzheimer s Research & Therapy • Apr 22, 2019

Authors:

Oskar Hansson

Sylvain Lehmann

Markus Otto

Abstract

The cerebrospinal fluid (CSF) biochemical markers (biomarkers) Amyloidβ 42 (Aβ42), total Tau (T-tau) and Tau phosphorylated at threonine 181 (P-tau181) have proven diagnostic accuracy for mild cognitive impairment and dementia due to Alzheimer’s Disease (AD). In an effort to improve the accuracy of ...

Subject

Neurology

Geriatric psychiatry

Medicine

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