Benralizumab for the Prevention of COPD Exacerbations

J. Criner, Gerard; R. Celli, Bartolomé; E. Brightling, Christopher; Agustí, Àlvar; Papi, Alberto; Singh, Dave; D. Sin, Don; Vogelmeier, Claus; C. Sciurba, Frank; Bafadhel, Mona; Backer, Vibeke; Kato, Motokazu; Ramírez‐Venegas, Alejandra; Wei, Yu-Feng; Bjermer, Leif; H. Shih, Vivian; Jison, Maria; O’Quinn, Sean; Makulova, Natalya; Newbold, Paul; Goldman, Mitchell; J. Martin, Ubaldo

doi:10.1056/nejmoa1905248

Public

Benralizumab for the Prevention of COPD Exacerbations

Published in New England Journal of Medicine • May 20, 2019

Authors:

Gerard J. Criner

Bartolomé R. Celli

Christopher E. Brightling

Abstract

BACKGROUND: The efficacy and safety of benralizumab, an interleukin-5 receptor alpha-directed cytolytic monoclonal antibody, for the prevention of exacerbations in patients with moderate to very severe chronic obstructive pulmonary disease (COPD) are not known. METHODS: In the GALATHEA and TERRANOVA...

Subject

Benralizumab

COPD

Medicine

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