Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts

Alexander, M; Katrina Loomis, A.; van der Lei, Johan; Duarte‐Salles, Talita; Prieto‐Alhambra, Daniel; Ansell, David; Pasqua, Alessandro; Lapi, Francesco; R. Rijnbeek, Peter; Mosseveld, Mees; Waterworth, Dawn; Kendrick, Stuart; Sattar, Naveed; Alazawi, William

doi:10.1186/s12916-019-1321-x

Public

Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts

Published in BMC Medicine • May 19, 2019

Authors:

M Alexander

A. Katrina Loomis

Johan van der Lei

Abstract

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a common condition that progresses in some patients to steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma (HCC). Here we used healthcare records of 18 million adults to estimate risk of acquiring advanced liver disease diagnoses in...

Subject

Medicine

Hepatocellular carcinoma

Cirrhosis

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