CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p.
Published in Journal of experimental & clinical cancer research : CR • Jan 24, 2019
Authors:,,
Xinfeng Yu
Dong Wang
Xiaohui Wang
Abstract
BACKGROUND: Activation of CXCL12/CXCR4 axis has been found to be associated with invasion and metastasis in many cancers. However, the underlying mechanism remains elusive. Increasing data highlight that non-coding RNAs are linked to CRC progression. METHODS: The effects of CXCR4 were investigated u...