Ferroptosis inhibitor alleviates Radiation-induced lung fibrosis (RILF) via down-regulation of TGF-β1

Li, Xuan; Duan, Lijie; Yuan, Sujuan; Zhuang, Xibing; Qiao, Tiankui; He, Jian

doi:10.1186/s12950-019-0216-0

Public

Ferroptosis inhibitor alleviates Radiation-induced lung fibrosis (RILF) via down-regulation of TGF-β1

Published in Journal of Inflammation • May 29, 2019

Authors:

Xuan Li

Lijie Duan

Sujuan Yuan

Abstract

BACKGROUND: Radiation-induced lung fibrosis (RILF) is a severe and life-threatening complication of thoracic radiotherapy. Cell death is the key issue in RILF. Ferroptosis is a form programmed cell death implicated in the pathologies of inflammation. This study aimed to investigate the role of ferro...

Subject

Sirius Red

Western blot

Fibrosis

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