Synthesis of Copper Peroxide Nanodots for H<sub>2</sub>O<sub>2</sub> Self-Supplying Chemodynamic Therapy

Lin, Lisen; Huang, Tao; Song, Jibin; Ou, Xiangyu; Wang, Zhangtong; Deng, Hongzhang; Tian, Rui; Liu, Yijing; Wang, Junfeng; Liu, Yuan; Yu, Guocan; Zhou, Zijian; Wang, Sheng; Niu, Gang; Yang, Huanghao; Chen, Xiaoyuan

doi:10.1021/jacs.9b03457

Public

Synthesis of Copper Peroxide Nanodots for H2O2 Self-Supplying Chemodynamic Therapy

Published in Journal of the American Chemical Society • Jun 2, 2019

Authors:

Lisen Lin

Tao Huang

Jibin Song

Abstract

Chemodynamic therapy (CDT) employs Fenton catalysts to kill cancer cells by converting intracellular H 2 O 2 into hydroxyl radical (•OH), but endogenous H 2 O 2 is insufficient to achieve satisfactory anticancer efficacy. Despite tremendous efforts, engineering CDT agents with specific and efficient...

Subject

Chemistry

Endocytosis

Nanodot

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