Development and Validation of a New Risk Prediction Score for Life-Threatening Ventricular Tachyarrhythmias in Laminopathies

Wahbi, Karim; Ben Yaou, Rabah; Gandjbakhch, Estelle; Anselme, Frédéric; Gossios, Thomas; K. Lakdawala, Neal; Stalens, Caroline; Sacher, Frédéric; Babuty, Dominique; Trochu, Jean‐Noël; Moubarak, Ghassan; Savvatis, Kostantinos; Porcher, Raphaël; Laforêt, Pascal; Fayssoil, Abdallah; Marijon, Éloi; Stojkovic, Tanya; Béhin, Anthony; Léonard-Louis, Sarah; Solé, Guilhem; Labombarda, Fabien; Richard, Pascale; Métay, Corinne; Quijano-Roy, Susana; Dabaj, Ivana; Klug, Didier; Vantyghem, Marie‐Christine; Chevalier, Philippe; Ambrosi, Pı̈erre; Salort, Emmanuelle; Sadoul, Nicolas; Waintraub, Xavier; Chikhaoui, Khadija; Mabo, Philippe; Combes, Nicolas; Maury, Philippe; Sellal, Jean‐Marc; B. Tedrow, Usha; M. Kalman, Jonathan; K. Vohra, Jitendra; F.A. Androulakis, Alexander; Zeppenfeld, Katja; Thompson, Tina; Barnérias, Christine; Bécane, Henri-Marc; Bieth, Éric; Boccara, Franck; Bonnet, Damien; Bouhour, Françoise; Boulé, Stéphane; Bréhin, Anne‐Claire; Chapon, Françoise; Cintas, Pascal; Cuisset, Jean‐Marie; Davy, Jean‐Marc; De Sandre‐Giovannoli, Annachiara; Démurger, Florence; Desguerre, Isabelle; Dieterich, Klaus; Durigneux, Julien; Echaniz‐Laguna, Andoni; Eschalier, Romain; Ferreiro, Ana; Ferrer, Xavier; Francannet, Christine; Fradin, Mélanie; Gaborit, Bénédicte; Gay, Arnaud; Hagège, Albert; Isapof, Arnaud; Jéru, Isabelle; Juntas Morales, Raúl; Lagrue, Emmanuelle; Lamblin, Nicolas; Lascols, Olivier; Laugel, Vincent; Lazarus, Arnaud; Leturcq, France; Lévy, Nicolas; Magot, Armelle; Manel, Véronique; P. Martins, Raphaël; Mayer, M.; Mercier, Sandra; Meune, Christophe; Michaud, Maud; Minot-Myhié, Marie-Christine; Muchir, Antoine; Nadaj‐Pakleza, Aleksandra; Péréon, Yann; Petiot, Philippe; Petit, Florence; Praline, Julien; Rollin, Anne; Sabouraud, Pascal; Sarret, Catherine; Schaeffer, S.; Taithe, Frédéric; Tard, Céline; Tiffreau, V.; Toutain, Annick; Vatier, Camille; Walther‐Louvier, Ulrike; Eymard, B.; Charron, Philippe; Vigouroux, Corinne; Bonne, Gisèle; Kumar, Saurabh; Elliott, Perry; Duboc, Denis

doi:10.1161/circulationaha.118.039410

Public

Development and Validation of a New Risk Prediction Score for Life-Threatening Ventricular Tachyarrhythmias in Laminopathies

Published in Circulation • Jun 3, 2019

Authors:

Karim Wahbi

Rabah Ben Yaou

Estelle Gandjbakhch

Abstract

BACKGROUND: An accurate estimation of the risk of life-threatening (LT) ventricular tachyarrhythmia (VTA) in patients with LMNA mutations is crucial to select candidates for implantable cardioverter-defibrillator implantation. METHODS: We included 839 adult patients with LMNA mutations, including 66...

Subject

Medicine

Internal medicine

Cardiology

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