A major role for common genetic variation in anxiety disorders

L. Purves, Kirstin; R. I. Coleman, Jonathan; Meier, Sandra; Rayner, Christopher; A. S. Davis, Katrina; Cheesman, Rosa; Bækvad‐Hansen, Marie; D. Børglum, Anders; Wan Cho, Shing; Deckert, Jürgen; A. Gaspar, Héléna; Bybjerg‐Grauholm, Jonas; M. Hettema, John; Hotopf, Matthew; M. Hougaard, David; Hübel, Christopher; Kan, Carol; M. McIntosh, Andrew; Mors, Ole; Bo Mortensen, Preben; Nordentoft, Merete; Werge, Thomas; K. Nicodemus, Kristin; Mattheisen, Manuel; Breen, Gerome; C. Eley, Thalia

doi:10.1038/s41380-019-0559-1

Public

A major role for common genetic variation in anxiety disorders

Published in Molecular Psychiatry • Nov 20, 2019

Authors:

Kirstin L. Purves

Jonathan R. I. Coleman

Sandra Meier

Abstract

Anxiety disorders are common, complex psychiatric disorders with twin heritabilities of 30–60%. We conducted a genome-wide association study of Lifetime Anxiety Disorder ( n case = 25 453, n control = 58 113) and an additional analysis of Current Anxiety Symptoms ( n case = 19 012, n control = 58 11...

Subject

Anxiety

Variation (astronomy)

Psychology

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