Effect of 5- trans isomer of arachidonic acid on model liposomal membranes studied by a combined simulation and experimental approach

Tremi, Ioanna; F. Anagnostopoulos, D.; Spyratou, Ellas; Gkeka, Paraskevi; G. Georgakilas, Alexandros; Chatgilialoglu, Chryssostomos; Cournia, Zoe

doi:10.1101/279422

Public

Effect of 5- trans isomer of arachidonic acid on model liposomal membranes studied by a combined simulation and experimental approach

Published in bioRxiv (Cold Spring Harbor Laboratory) • Mar 9, 2018

Authors:

Ioanna Tremi

D. F. Anagnostopoulos

Ellas Spyratou

Abstract

Abstract Unsaturated fatty acids are found in humans predominantly in the cis configuration. Fatty acids in the trans configuration are primarily the result of human processing ( trans fats), but can also be formed endogenously by radical stress. The cis-trans isomerization of fatty acids by free ra...

Subject

Isomerization

Arachidonic acid

Membrane

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