Structural basis for cooperativity of human monoclonal antibodies to meningococcal factor H-binding protein

Abstract Monoclonal antibody (mAb) cooperativity is a phenomenon triggered when mAbs couples promote increased bactericidal killing compared to individual partners. Cooperativity has been deeply investigated among mAbs elicited by factor H-binding protein (fHbp), a Neisseria meningitidis surface-exp... View More