Effectiveness and Safety of Bronchial Thermoplasty in the Treatment of Severe Asthma: A Multicenter, Randomized, Double-Blind, Sham-Controlled Clinical Trial

Castro, Mario; S. Rubin, Adalberto; Laviolette, Michel; Fiterman, Jussara; De Andrade Lima, Marina; L. Shah, Pallav; Fiss, Elie; Olivenstein, Ronald; C. Thomson, Neil; M. Niven, Robert; D. Pavord, Ian; Simoff, Michael; R. Duhamel, David; McEvoy, Charlene; Barbers, Richard; H.T. ten Hacken, Nicolaas; E. Wechsler, Michael; Holmes, Mark; J. Phillips, Martin; Erzurum, Serpil; Lunn, William; Israel, Elliot; Jarjour, Nizar; Kraft, Monica; S. Shargill, Narinder; Quiring, John; M. Berry, Scott; Cox, Gerard

doi:10.1164/rccm.200903-0354oc

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Effectiveness and Safety of Bronchial Thermoplasty in the Treatment of Severe Asthma: A Multicenter, Randomized, Double-Blind, Sham-Controlled Clinical Trial

Shared by NobleBlocks on Jan 1, 2010 • 12:00 AM UTC

Authors:

Mario Castro

Adalberto S. Rubin

Michel Laviolette

Abstract

Abstract Rationale Bronchial thermoplasty (BT) is a bronchoscopic procedure in which controlled thermal energy is applied to the airway wall to decrease smooth muscle. Objectives To evaluate the effectiveness and safety of BT versus a sham procedure in subjects with severe asthma who remain symptoma...

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