A variant erythroferrone disrupts iron homeostasis in <i>SF3B1</i> -mutated myelodysplastic syndrome

Bondu, Sabrina; Alary, Anne‐Sophie; Lefèvre, Carine; Houy, Alexandre; Jung, Grace; Lefèbvre, Thibaud; Rombaut, David; Boussaid, Ismaël; Bousta, Abderrahmane; Guillonneau, François; Perrier, Prunelle; Alsafadi, Samar; Wassef, Michel; Margueron, Raphaël; Rousseau, Alice; Droin, Nathalie; Cagnard, Nicolas; Kaltenbach, Sophie; Winter, Susann; Sophie Kubasch, Anne; Bouscary, Didier; Santini, Valeria; Toma, Andréa; Hunault, Mathilde; Stamatoullas, Aspasia; Gyan, Emmanuel; Cluzeau, Thomas; Platzbecker, Uwe; Adès, Lionel; Puy, Hervé; Stern, Marc‐Henri; Karim, Zoubida; Mayeux, Patrick; Nemeth, Elizabeta; Park, Sophie; Ganz, Tomas; Kautz, Léon; Kosmider, Olivier; Fontenay, Michaëla

doi:10.1126/scitranslmed.aav5467

Public

A variant erythroferrone disrupts iron homeostasis in SF3B1 -mutated myelodysplastic syndrome

Published in Science Translational Medicine • Jul 10, 2019

Authors:

Sabrina Bondu

Anne‐Sophie Alary

Carine Lefèvre

Abstract

-mutated erythroblasts decreased in lenalidomide-responsive anemic patients, identifying variant ERFE as a specific biomarker of clonal erythropoiesis.

Subject

Hepcidin

Iron homeostasis

Homeostasis

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!