The lncRNA PVT1 regulates nasopharyngeal carcinoma cell proliferation via activating the KAT2A acetyltransferase and stabilizing HIF-1α

Wang, Ying; Chen, Wanyuan; Lian, Jiayan; Zhang, Haibo; Yu, Bo; Zhang, Minjun; Wei, Fangqiang; Wu, Jianhui; Jiang, Jiaxiang; Jia, Yongshi; Mo, Fan; Zhang, Shirong; Liang, Xiaodong; Mou, Xiaozhou; Tang, Jianming

doi:10.1038/s41418-019-0381-y

Public

The lncRNA PVT1 regulates nasopharyngeal carcinoma cell proliferation via activating the KAT2A acetyltransferase and stabilizing HIF-1α

Published in Cell Death and Differentiation • Jul 18, 2019

Authors:

Ying Wang

Wanyuan Chen

Jiayan Lian

Abstract

Long noncoding RNAs (lncRNAs) play important roles in regulating the development and progression of many cancers. However, the clinical significance of specific lncRNAs in the context of nasopharyngeal carcinoma (NPC) and the molecular mechanisms by which they regulate this form of cancer remain lar...

Subject

PVT1

Nasopharyngeal carcinoma

Cancer research

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