Evolving concepts in bone infection: redefining “biofilm”, “acute vs. chronic osteomyelitis”, “the immune proteome” and “local antibiotic therapy”

A. Masters, Elysia; P. Trombetta, Ryan; L. de Mesy Bentley, Karen; F. Boyce, Brendan; Gill, Ann; R. Gill, Steven; Nishitani, Kohei; Ishikawa, Masahiro; Morita, Y.; Ito, Hiromu; N. Bello‐Irizarry, Sheila; Ninomiya, Mark; D. Brodell, James; C. Lee, Charles; P. Hao, Stephanie; Oh, Irvin; Xie, Chao; A. Awad, Hani; L. Daiss, John; R. Owen, John; L. Kates, Stephen; M. Schwarz, Edward; Muthukrishnan, Gowrishankar

doi:10.1038/s41413-019-0061-z

Public

Evolving concepts in bone infection: redefining “biofilm”, “acute vs. chronic osteomyelitis”, “the immune proteome” and “local antibiotic therapy”

Published in Bone Research • Jul 15, 2019

Authors:

Elysia A. Masters

Ryan P. Trombetta

Karen L. de Mesy Bentley

Abstract

Abstract Osteomyelitis is a devastating disease caused by microbial infection of bone. While the frequency of infection following elective orthopedic surgery is low, rates of reinfection are disturbingly high. Staphylococcus aureus is responsible for the majority of chronic osteomyelitis cases and i...

Subject

Osteomyelitis

Bone Infection

Staphylococcus aureus

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