Initial steps in reconstruction of the human ovary: survival of pre-antral stage follicles in a decellularized human ovarian scaffold

Elisabeth Pors, Susanne; Ramløse, Maja; Nikiforov, Dmitry; Lundsgaard, K; Cheng, Jiumei; Yding Andersen, Claus; Gry Kristensen, Stine

doi:10.1093/humrep/dez077

Public

Initial steps in reconstruction of the human ovary: survival of pre-antral stage follicles in a decellularized human ovarian scaffold

Published in Human Reproduction • Apr 29, 2019

Authors:

Susanne Elisabeth Pors

Maja Ramløse

Dmitry Nikiforov

Abstract

STUDY QUESTION: Can a reconstructed ovary using decellularized human ovarian tissue (DCT) support survival of pre-antral stage follicles? SUMMARY ANSWER: We have demonstrated an effective protocol for decellularization of human ovarian tissues and successful recellularization with isolated human ova...

Subject

Decellularization

Ovary

Antral follicle

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