Granulocytic Myeloid‐Derived Suppressor Cells Promote the Stemness of Colorectal Cancer Cells through Exosomal S100A9

Wang, Yungang; Yin, Kai; Tian, Jie; Xia, Xueli; Ma, Jie; Tang, Xinyi; Xu, Huaxi; Wang, Shengjun

doi:10.1002/advs.201901278

Public

Granulocytic Myeloid‐Derived Suppressor Cells Promote the Stemness of Colorectal Cancer Cells through Exosomal S100A9

Published in Advanced Science • Jul 22, 2019

Authors:

Yungang Wang

Kai Yin

Jie Tian

Abstract

Cancer stem cells play a critical role in colorectal cancer (CRC) progression. Myeloid-derived suppressor cells (MDSCs) promote tumor progression through multiple mechanisms in CRC. The roles of MDSCs in CRC cell stemness are unclear. MDSC-derived exosomes are proposed to act as intercellular messen...

Subject

Microvesicles

Cancer research

Myeloid-derived Suppressor Cell

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