Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): patterns of recurrence and post-hoc survival analysis of a randomised phase 3 trial

M. de Boer, Stephanie; Powell, Melanie; Mileshkin, Linda; Katsaros, Dionyssios; Bessette, Paul; Haie-Méder, Christine; B. Ottevanger, Petronella; A. Ledermann, Jonathan; Khaw, Pearly; D’Amico, Romerai; Fyles, Anthony; Baron, Marie‐Hélène; M. Jürgenliemk‐Schulz, Ina; C Kitchener, Henry; W. Nijman, Hans; Wilson, Godfrey; A. Brooks, Susan; Gribaudo, Sergio; Provencher, Diane; Hanzen, C.; F.P.M. Kruitwagen, Roy; T.H.B.M. Smit, Vincent; Singh, Naveena; Do, Viet; Alberto Lissoni, Andrea; A. Nout, Remi; Feeney, Amanda; Verhoeven-Adema, Karen; Putter, Hein; L. Creutzberg, Carien; McCormack, Mary; Whitmarsh, Karen; Allerton, R.; Gregory, D.; Symonds, Paul; Hoskin, Peter; Adusumalli, Madhavi; Anand, Anjana; Wade, Robert; Stewart, Alexandra; Chris Taylor, W.; Lutgens, LCHW; Hollema, Harry; Pras, E.; Snyers, An; Westerveld, Henrike; Jobsen, JJ; Slot, Annerie; Mens, JM; Stam, TC; van Triest, Baukelien; van der Steen-Banasik, E.; Winter, K.; Quinn, MA; Kolodziej, Ilka; Pyman, Jan; Johnson, Carol; Capp, Anne; Fossati, Roldano; Colombo, Alessandro; Carinelli, Silvestro; Ferrero, Annamaria; Artioli, Grazia; Davidson, Catherine; Meg McLachlin, C.; Ghatage, Prafull; Rittenberg, PVC; Souhami, Luís; Thomas, Gillian; Duvillard, Pierre; Berton-Rigaud, D; Tubiana-Mathieu, N.

doi:10.1016/s1470-2045(19)30395-x

Public

Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): patterns of recurrence and post-hoc survival analysis of a randomised phase 3 trial

Published in The Lancet Oncology • Jul 22, 2019

Authors:

Stephanie M. de Boer

Melanie Powell

Linda Mileshkin

Abstract

BACKGROUND: The PORTEC-3 trial investigated the benefit of combined adjuvant chemotherapy and radiotherapy versus pelvic radiotherapy alone for women with high-risk endometrial cancer. We updated the analysis to investigate patterns of recurrence and did a post-hoc survival analysis. METHODS: given ...

Subject

Medicine

Endometrial cancer

Radiation therapy

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