Concordance between the assessment of Aβ42, T‐tau, and P‐T181‐tau in peripheral blood neuronal‐derived exosomes and cerebrospinal fluid

Jia, Longfei; Qiu, Qiongqiong; Zhang, Heng; Chu, Lan; Du, Yifeng; Zhang, Jiewen; Zhou, Chunkui; Liang, Furu; Shi, Shengliang; Wang, Shan; Qin, Wei; Wang, Qi; Li, Fangyu; Wang, Qigeng; Li, Yan; Shen, Luxi; Wei, Yiping; Jia, Jianping

doi:10.1016/j.jalz.2019.05.002

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Concordance between the assessment of Aβ42, T‐tau, and P‐T181‐tau in peripheral blood neuronal‐derived exosomes and cerebrospinal fluid

Published in Alzheimer s & Dementia • Aug 1, 2019

Authors:

Longfei Jia

Qiongqiong Qiu

Heng Zhang

Abstract

INTRODUCTION: Neuronal-derived exosomal Aβ42, T-tau, and P-T181-tau have been demonstrated to be biomarkers of Alzheimer's disease (AD). However, no study has assessed the association of Aβ42, T-tau, and P-T181-tau between exosomes and CSF. METHODS: This was a multicenter study with two-stage design...

Subject

Cerebrospinal fluid

Microvesicles

Biomarker

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