A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial

Façon, Thierry; Α. Dimopoulos, Meletios; Meuleman, Nathalie; Belch, Andrew; Mohty, Mohamad; Chen, Wen‐Ming; Kım, Kihyun; Zamagni, Elena; Rodríguez‐Otero, Paula; Renwick, William; Rosé, Christian; Tempescul, Adrian; M. Boyle, Eileen; Manier, Salomon; Attal, Michel; Moreau, Philippe; Macro, Margaret; Leleu, Xavier; Lorraine Chrétien, Marie; Ludwig, Heinz; Guo, Shien; Sturniolo, Michael; Tinel, Antoine; Silvia Monzini, Mara; Costa, Bruno; Houck, Vanessa; Hulin, Cyrille; Yves Mary, Jean

doi:10.1038/s41375-019-0539-0

Public

A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial

Published in Leukemia • Aug 19, 2019

Authors:

Thierry Façon

Meletios Α. Dimopoulos

Nathalie Meuleman

Abstract

Patients with multiple myeloma are generally older and vary in fitness levels, which may influence the clinical benefit of treatment. Patients from the large, phase 3 FIRST trial in newly diagnosed multiple myeloma (NDMM) were retrospectively investigated to determine outcomes based on frailty using...

Subject

Multiple myeloma

Medicine

Internal medicine

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