pH-Switchable Antimicrobial Nanofiber Networks of Hydrogel Eradicate Biofilm and Rescue Stalled Healing in Chronic Wounds

Wang, Jianhao; Chen, Xiaoyi; Zhao, Yuan; Yang, Yanmei; Wang, Weijie; Chun, Wu; Yang, Baozhu; Zhang, Zhaotian; W. Zhang, Leshuai; Liu, Yun; Du, Xuancheng; Li, Weifeng; Qiu, Lin; Jiang, Pengju; Mou, Xiaozhou; Li, Yongqiang

doi:10.1021/acsnano.9b05608

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pH-Switchable Antimicrobial Nanofiber Networks of Hydrogel Eradicate Biofilm and Rescue Stalled Healing in Chronic Wounds

Published in ACS Nano • Sep 6, 2019

Authors:

Jianhao Wang

Xiaoyi Chen

Yuan Zhao

Abstract

Biofilm infections can induce chronic inflammation and stall the normal orchestrated course of wound-healing cascades. Herein, pH-switchable antimicrobial hydrogel with nanofiber networks for biofilm eradication and rescuing stalled healing in chronic wounds is reported on the basis of the self-asse...

Subject

Biofilm

Nanofiber

Antimicrobial

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