Knockdown of circDENND4C inhibits glycolysis, migration and invasion by up-regulating miR-200b/c in breast cancer under hypoxia

Ren, Shasha; Liu, Jiuzhou; Feng, Yun; Li, Zhenyu; He, Liang; Li, Leilei; Cao, Xiaozhong; Wang, Zhenghua; Zhang, Yanwu

doi:10.1186/s13046-019-1398-2

Public

Knockdown of circDENND4C inhibits glycolysis, migration and invasion by up-regulating miR-200b/c in breast cancer under hypoxia

Published in Journal of Experimental & Clinical Cancer Research • Sep 5, 2019

Authors:

Shasha Ren

Jiuzhou Liu

Yun Feng

Abstract

BACKGROUND: Hypoxia is a key feature of breast cancer, which affects cancer development, metastasis and metabolism. Previous studies suggested that circular RNAs (circRNAs) could participate in cancer progression and hypoxia regulation. This study aimed to investigate the role of circRNA differentia...

Subject

Gene knockdown

Breast cancer

Cancer research

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