Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial

J. Hausenloy, Derek; Kharbanda, Rajesh; Møller, Ulla; Ramlall, Manish; Aarøe, Jens; J. Butler, Robert; Bulluck, Heerajnarain; Clayton, Tim; Dana, Ali; Dodd, Matthew; Engstrøm, Thomas; D. Evans, Richard; Flensted Lassen, Jens; Frischknecht Christensen, Erika; M. García‐Ruiz, José; A Gorog, Diana; Hjort, Jakob; F Houghton, Richard; Ibáñez, Borja; Knight, Rosemary; Lippert, Freddy; Thomsen Lønborg, Jacob; Mæng, Michael; Milasinovic, Dejan; More, Ranjit; M. Nicholas, Jennifer; Okkels Jensen, Lisette; Perkins, Alexander; Radovanović, Nebojša; Rakhit, Roby; Ravkilde, Jan; Ryding, Alisdair; Rahbek Schmidt, Michael; S. Riddervold, Ingunn; Toft Sørensen, Henrik; Stanković, Goran; Varma, Madhusudhan; Webb, Ian; Juhl Terkelsen, Christian; P. Greenwood, John; M. Yellon, Derek; Erik Bøtker, Hans; Junker, Anders; Kaltoft, Anne; Madsen, Morten; Høj Christiansen, Evald; Jakobsen, Lars; Carstensen, Steen; Dalby Kristensen, Steen; Thim, Troels; Møller Pedersen, Karin; Tidemand Korsgaard, Mette; Iversen, Allan; Jørgensen, Erik; R. Joshi, Francis; Pedersen, Frants; Henrik Tilsted, Hans; Alzuhairi, Karam; Saunamäki, Kari; Holmvang, Lene; Ahlehof, Ole; Sørensen, Rikke; Helqvist, Steffen; Màrk, B.; Boel Villadsen, Anton; Raungaard, Bent; Thuesen, Leif; Kirk Christiansen, Martin; Freeman, Philip; Eggert Jensen, Svend; Schmidt Skov, Charlotte; Aziz, Ahmed; Steen Hansen, Henrik; Ellert, Julia; Tange Veien, Karsten; Erik Pedersen, Knud; Hansen, Knud; Ahlehoff, Ole; Cappelen, Helle; Wittrock, Daniel; Anders Hansen, Poul; Peter Ankersen, Jens; Witting Hedegaard, Kim; Kempel, John; Kaus, Henning; Erntgaard, Dennis; Mejsner Pedersen, Danny; Giebner, Matthias; Martin Hansen, Troels; Radovanović, Mina; Prodanović, Maja; Savić, Lidija; Pejic, Marijana; Matić, Dragan; Ušćumlić, Ana; Subotić, Ida; Lasica, Ratko; Vukcevic, Vladan; Suárez, Alfonso; Samaniego, Beatriz; Morı́s, César; Segovia, Eduardo; Ernesto, Hernandez; Lozano, Íñigo; Pascual, Isaac; M. Vegas-Valle, José; Rozado, José; Rondán, Juan; Avanzas, Pablo; del Valle, Raquel; Padrón, Remigio; García-Castro, Alfonso; Cubillos Arango, A.; B. Medina-Cameán, Ana; I. Fente, Ana; Muriel-Velasco, Ana; Pomar-Amillo, Ángeles; L. Roza, César; M. Martínez-Fernández, César; Buelga-Díaz, Covadonga; Fernández-Gonzalo, David; Fernández, Elena; Díaz-González, Eloy; Martinez-González, Eugenio; Iglesias-Llaca, Fernando; M. Viribay, Fernando; J. Fernández-Mallo, Francisco; J. Hermosa, Francisco; Martínez-Bastida, Ginés; Goitia-Martín, Javier; L. Vega-Fernández, José; M. Tresguerres, Jose; A. Rodil-Díaz, Juan; Villar-Fernández, Lara; Alberdi, Lucila; Abella-Ovalle, Luis; de la Roz, Manuel; Fernández-Carral Fernández-Carral, Marcos; C. Naves, María; Peláez, M.Córdoba; Fuentes, M.; García-Alonso, María; Jesús García Villanueva, María; S. Vinagrero, María; Vázquez-Suárez, María; Martínez-Valle, Marta; Nonide, Marta; Pozo-López, Mónica; Bernardo-Alba, Pablo; Galván-Núñez, Pablo; J. Martínez-Pérez, Polácido; Castro, Rafael; Suárez-Coto, Raquel; Suárez-Noriega, Raquel; Guinea, Rocío; Bangueses Quintana, R; de Cima, Sara; A. Hedrera, Segundo; I. Laca, Sonia; Llorente-Álvarez, Susana; Pascual, Susana; Cimas, Teodorna; Mathur, Anthony; McFarlane-Henry, Eleanor; Leonard, Gerry; Veerapen, Jessry; Westwood, Mark; Colicchia, Martina; Prossora, Mary; Andiapen, Mervyn; Mohiddin, Saidi; Lenzi, Valentina; Hua Chong, Jun; Francis, Rohin; Pine, Amy; Jamieson-Leadbitter, Caroline; Neal, Debbie; Din, Jamilah; D. McLeod, Jane; Roberts, Josh; Poloková, Karin; Longman, Kristel; Penney, L.L.; Lakeman, Nicki; Wells, Nicki; Hopper, Oliver; Y Coward, P; O’Kane, Peter; Harkins, Ruth; Guyatt, Samantha; Kennard, Sarah; Orr, Sarah; Horler, Stephanie; Morris, Steve; Walvin, Tom; Snow, Tom; Cunnington, Michael; Burd, Amanda; Gowing, Anne; Krishnamurthy, Arvindra; Harland, Charlotte; R. Norfolk, D.; Johnstone, D; Newman, Hannah; L. Reed, Helen; P. O’Neill, James; P. 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Gue, Ying; Kanji, Rahim; Ryding, Alisdair; Ratcliffe, Amanda; Merrick, Angela; Horwood, Carol; Sarti, Charlotte; Maart, Clint; Moore, Donna; Dockerty, Francesca; Baucutt, Karen; Pitcher, Louise; Ilsley, Mary; Clarke, Millie; Germon, Rachel; Costa Gomes, Sara; Thomas, Clare; Nair, Sunil; Staines, Jocasta; Nicholson, Susan; Watkinson, Oliver; Gallagher, Ian; Nelthorpe, Faye; Musselwhite, Janine; Großer, Konrad; Stimson, Leah; Eaton, Michelle; Heppell, Richard; Turney, Sharon; Horner, Victoria; Schumacher, Natasha; Moon, Angela; Mota, Paula; O'Donnell, Joshua; Panicker, Abeesh; Musa, Anntoniette; Tapp, Luke; Krishnamoorthy, Suresh; Ansell, Valerie; Ali, Danish; Hyndman, Samantha; Banerjee, Prithwish; Been, Martin; Mackenzie, Ailie; McGregor, Andrew; Hildick‐Smith, David; Champney, Felicity; Ingoldby, Fiona; Keate, Kirstie; Bennett, Lorraine; Skipper, Nicola; Gregory, Sally; Harfield, Scott; Mudd, Alexandra; Wragg, Christopher; Barmby, David; Grech, Ever; Hall, Ian; Middle, Janet; Barker, Joann; Fofie, Joyce; Gunn, Julian; Housley, Kay; Cockayne, L; Weatherlley, Louise; Theodorou, Nana; Wheeldon, Nigel; Fati, Pene; F. 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Hoole, Stephen; Ramos, Angelo; Sevillano, Annaliza; Nicholson, Anne; Solieri, Ashley; Redman, Emily; Byrne, Jean; Joyce, Joan; Riches, Joanne; R. Davies, John; Allen, Kezia; Saclot, Louie; Ocampo, Madelaine; Vertue, Mark; Christmas, Natasha; Koothoor, Raiji; Gamma, Reto; Alvares, Wilson; Pepper, Stacey; Kobson, Barbara; Reeve, Christy; Malik, Iqbal; Chester, E.; Saunders, Heidi; Mojela, Idah; Smee, Joanna; Davies, Justin; Davies, Nina; Clifford, Piers; Dias, Priyanthi; Kaur, Ramandeep; Moreira, Sílvia; Ahmad, Yousif; Tomlinson, Lucy; Pengelley, Clare; Bidle, Amanda; Spence, Sharon; Al‐Lamee, Rasha; Phuyal, Urmila; Abbass, Hakam; Bose, Tuhina; Elliott, Rebecca; Foundun, Aboo; Chung, Alan; Freestone, Beth; Kaeng Lee, Dr; Mohamed Elshiekh, Dr; Pulikal, George; Bhatre, Gurbir; Douglas, James; Kaeng, Lee; Pitt, Mike; Watkins, Richard; Gill, Simrat; Hartley, Amy; Lucking, Andrew; Moreby, B.; Darby, Damaris; Corps, Ellie; Parsons, Georgina; De Mance, Gianluigi; Fahrai, Gregor; Turner, Jennifer; P. Langrish, Jeremy; Gaughran, Lisa; Wolyrum, Mathias; Azkhalil, Mohammed; Bates, Rachel; Given, Rachel; Kharbanda, Rajesh; Douthwaite, Rebecca; Lloyd, Steph; Neubauer, Stephen; Barker, Deborah; Dana, Ali; Suttling, Anne; Turner, Charlotte; Smith, Clare; Longbottom, Colin; David, Ross; Cunliffe, D.R.; R. Cox, Emily; Whitehead, Helena; Hudson, Karen; N. Jones, Leslie; Drew, Martin; Chant, N.S.; Haworth, Peter; Capel, Robert; Austin, Rosalynn; Howe, Serena; Smith, Trevor; Hobson, Alex; C. Strike, Philip; Griffiths, H.; Anantharam, Brijesh; Jack, Pearse; Thornton, Emma; B. Hodgson, Adrian; Jennison, Alan; McSkeane, Anna; Smith, Bethany; Shaw, Caroline; Leathers, Chris; Armstrong, Elissa; Carruthers, Gayle; Simpson, Holly; D. Smith, Jan; Hodierne, Jeremy; Kelly, Julie; Barclay, Justin; Scott, Kerry; Gregson, Lisa; Buchanan, Louise; McCormick, Louise; Varma, Madhusudhan; Kelsall, Nicci; Mcarthy, Rachel; E. Taylor, R.; F. Thompson, Rebecca; J. Shelton, Rhidian; K. 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doi:10.1016/s0140-6736(19)32039-2

Public

Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial

Published in The Lancet • Sep 6, 2019

Authors:

Derek J. Hausenloy

Rajesh Kharbanda

Ulla Møller

Abstract

BACKGROUND: Remote ischaemic conditioning with transient ischaemia and reperfusion applied to the arm has been shown to reduce myocardial infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). We investigated whether rem...

Subject

Medicine

Myocardial infarction

Internal medicine

Research Assistant

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