Prostate Cancer Risks for Male BRCA1 and BRCA2 Mutation Carriers: A Prospective Cohort Study

Nyberg, Tommy; Frost, Debra; Barrowdale, Daniel; Gareth Evans, D.; Bancroft, Elizabeth; Adlard, Julian; Ahmed, Munaza; Barwell, Julian; F. Brady, Angela; Brewer, Carole; Cook, Jackie; Davidson, Rosemarie; Donaldson, Alan; Eason, Jacqueline; Gregory, Helen; Henderson, Alex; Izatt, Louise; J. Kennedy, Michael; Miller, Claire; J. Morrison, Patrick; Murray, Alex; Ong, Kai‐Ren; Porteous, Mary; Pottinger, Caroline; T. Rogers, Mark; Side, Lucy; Snape, Katie; Walker, Lisa; Tischkowitz, Marc; A. Eeles, Rosalind; F. Easton, Douglas; C. Antoniou, Antonis

doi:10.1016/j.eururo.2019.08.025

Public

Prostate Cancer Risks for Male BRCA1 and BRCA2 Mutation Carriers: A Prospective Cohort Study

Published in European Urology • Sep 6, 2019

Authors:

Tommy Nyberg

Debra Frost

Daniel Barrowdale

Abstract

BACKGROUND: BRCA1 and BRCA2 mutations have been associated with prostate cancer (PCa) risk but a wide range of risk estimates have been reported that are based on retrospective studies. OBJECTIVE: To estimate relative and absolute PCa risks associated with BRCA1/2 mutations and to assess risk modifi...

Subject

Medicine

Hazard ratio

Relative risk

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