Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention

Aiello, Anna; Farzaneh, Farzin; Candore, Giuseppina; Caruso, Calogero; Davinelli, Sergio; Maria Gambino, Caterina; Emanuela Ligotti, Mattia; Zareian, Nahid; Accardi, Giulia

doi:10.3389/fimmu.2019.02247

Public

Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention

Published in Frontiers in Immunology • Sep 25, 2019

Authors:

Anna Aiello

Farzin Farzaneh

Giuseppina Candore

Abstract

Aging is accompanied by remodeling of the immune system. With time, this leads to a decline in immune efficacy, resulting in increased vulnerability to infectious diseases, diminished responses to vaccination, and a susceptibility to age-related inflammatory diseases. An age-associated immune altera...

Subject

Immunosenescence

Immune system

Inflammation

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