Lysyl oxidases: from enzyme activity to extracellular matrix cross-links.
Published in Essays in biochemistry • Sep 13, 2019
Authors:,
Sylvain D Vallet
Sylvie Ricard-Blum
Abstract
The lysyl oxidase family comprises five members in mammals, lysyl oxidase (LOX) and four lysyl oxidase like proteins (LOXL1-4). They are copper amine oxidases with a highly conserved catalytic domain, a lysine tyrosylquinone cofactor, and a conserved copper-binding site. They catalyze the first step...
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