First-in-Man Study of a Cardiac Extracellular Matrix Hydrogel in Early and Late Myocardial Infarction Patients

H. Traverse, Jay; D. Henry, Timothy; Dib, Nabil; Patel, Amit; J. Pepine, Carl; L. Schaer, Gary; A. DeQuach, Jessica; M. Kinsey, Adam; Chamberlin, Paul; L. Christman, Karen

doi:10.1016/j.jacbts.2019.07.012

Public

First-in-Man Study of a Cardiac Extracellular Matrix Hydrogel in Early and Late Myocardial Infarction Patients

Published in JACC Basic to Translational Science • Sep 11, 2019

Authors:

Jay H. Traverse

Timothy D. Henry

Nabil Dib

Abstract

This study evaluated the safety and feasibility of transendocardial injections of VentriGel, a cardiac extracellular matrix hydrogel, in early and late post-myocardial infarction (MI) patients with left ventricular (LV) dysfunction. VentriGel was delivered in 15 patients with moderate LV dysfunction...

Subject

Extracellular matrix

Myocardial infarction

Cardiology

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