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The role of pyroptosis in cancer: pro-cancer or pro-"host"?

Published in Cell death & disease • Sep 9, 2019
Authors:
Xiaojing Xia
,
Xin Wang
,
Zhe Cheng

Abstract

Programmed cell death (PCD) refers to the way in which cells die depending on specific genes encoding signals or activities. Apoptosis, autophagy, and pyroptosis are all mechanisms of PCD. Among these mechanisms, pyroptosis is mediated by the gasdermin family, accompanied by inflammatory and immune ...

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