Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials

Yu, Jin‐Tai; Xu, Wei; Tan, Chen‐Chen; Andrieu, Sandrine; Suckling, John; Εvangelou, Εvangelos; Pan, An; Zhang, Can; Jia, Jianping; Feng, Lei; Heok Kua, Ee; Wang, Yan‐Jiang; Wang, Hui-Fu; Tan, Meng‐Shan; Li, Jieqiong; Hou, Xiao‐He; Wan, Yu; Tan, Lin; Mok, Vincent; Tan, Lan; Dong, Qiang; Touchon, Jacques; Gauthier, Serge; Aisen, Paul; Vellas, Bruno

doi:10.1136/jnnp-2019-321913

Public

Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials

Published in Journal of Neurology Neurosurgery & Psychiatry • Jul 20, 2020

Authors:

Jin‐Tai Yu

Wei Xu

Chen‐Chen Tan

Abstract

BACKGROUND: Evidence on preventing Alzheimer's disease (AD) is challenging to interpret due to varying study designs with heterogeneous endpoints and credibility. We completed a systematic review and meta-analysis of current evidence with prospective designs to propose evidence-based suggestions on ...

Subject

Observational study

Meta-analysis

Medicine

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