Ceftolozane/Tazobactam vs Polymyxin or Aminoglycoside-based Regimens for the Treatment of Drug-resistant Pseudomonas aeruginosa.

JM, Pogue; KS, Kaye; MP, Veve; TS, Patel; AT, Gerlach; SL, Davis; LA, Puzniak; TM, File; S, Olson; S, Dhar; RA, Bonomo; F, Perez

doi:10.1093/cid/ciz816

Public

Ceftolozane/Tazobactam vs Polymyxin or Aminoglycoside-based Regimens for the Treatment of Drug-resistant Pseudomonas aeruginosa.

Shared by NobleBlocks on Jul 1, 2020 • 12:00 AM UTC

Authors:

Pogue JM

Kaye KS

Veve MP

Abstract

Background Ceftolozane/tazobactam is a novel cephalosporin/beta-lactamase inhibitor combination that often retains activity against resistant Pseudomonas aeruginosa. The comparative safety and efficacy vs polymyxins or aminoglycosides in this setting remains unknown.Methods A retrospective, multicen...

Subject

Pseudomonas

Aminoglycoside

Polymyxin

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