Relapse Prevention with Tyrosine Kinase Inhibitors after Allogeneic Transplantation for Philadelphia Chromosome–Positive Acute Lymphoblast Leukemia: A Systematic Review

Warraich, Zabih; Tenneti, Pavan; Thai, Theresa; Hubben, Anne; Amin, Hina; McBride, Ali; Warraich, Sami; Hannan, Abdul; Hassan Warraich, Faiza; S. Majhail, Navneet; Kalaycio, Matt; Anwer, Faiz

doi:10.1016/j.bbmt.2019.09.022

Public

Relapse Prevention with Tyrosine Kinase Inhibitors after Allogeneic Transplantation for Philadelphia Chromosome–Positive Acute Lymphoblast Leukemia: A Systematic Review

Published in Biology of Blood and Marrow Transplantation • Sep 23, 2019

Authors:

Zabih Warraich

Pavan Tenneti

Theresa Thai

Abstract

Relapse after stem cell transplantation for Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) remains a significant challenge. In this systematic review, we compare survival outcomes of second-generation tyrosine kinase inhibitors (TKIs) nilotinib and dasatinib with first-gen...

Subject

Medicine

Lymphoblast

Philadelphia chromosome

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