Zika virus enhances monocyte adhesion and transmigration favoring viral dissemination to neural cells.

NV, Ayala-Nunez; G, Follain; F, Delalande; A, Hirschler; E, Partiot; GL, Hale; BC, Bollweg; J, Roels; M, Chazal; F, Bakoa; M, Carocci; S, Bourdoulous; O, Faklaris; SR, Zaki; A, Eckly; B, Uring-Lambert; F, Doussau; S, Cianferani; C, Carapito; FMJ, Jacobs; N, Jouvenet; JG, Goetz; R, Gaudin

doi:10.1038/s41467-019-12408-x

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Zika virus enhances monocyte adhesion and transmigration favoring viral dissemination to neural cells.

Shared by NobleBlocks on Sep 27, 2019 • 12:00 AM UTC

Authors:

Ayala-Nunez NV

Follain G

Delalande F

Abstract

Zika virus (ZIKV) invades and persists in the central nervous system (CNS), causing severe neurological diseases. However the virus journey, from the bloodstream to tissues through a mature endothelium, remains unclear. Here, we show that ZIKV-infected monocytes represent suitable carriers for viral...

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