Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma

Gao, Qiang; Zhu, Hongwen; Dong, Liangqing; Shi, Weiwei; Chen, Ran; Song, Zhijian; Huang, Chen; Li, Junqiang; Dong, Xiaowei; Zhou, Yanting; Liu, Qian; Ma, Lijie; Wang, Xiaoying; Zhou, Jian; Liu, Yansheng; S. Boja, Emily; I. Robles, Ana; Ma, Weiping; Wang, Pei; Li, Yize; Ding, Li; Wen, Bo; Zhang, Bing; Rodriguez, Henry; Gao, Daming; Zhou, Hu; Fan, Jia

doi:10.1016/j.cell.2019.08.052

Public

Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma

Published in Cell • Oct 1, 2019

Authors:

Qiang Gao

Hongwen Zhu

Liangqing Dong

Abstract

We performed the first proteogenomic characterization of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) using paired tumor and adjacent liver tissues from 159 patients. Integrated proteogenomic analyses revealed consistency and discordance among multi-omics, activation status of key ...

Subject

Hepatocellular carcinoma

Biology

Proteogenomics

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