Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

Chronic Kidney Disease Study, German; Tin, Adrienne; Cohort Study, Lifelines; A. Million Veteran Program, V.; Marten, Jonathan; L. Halperin Kuhns, Victoria; Li, Yong; Wuttke, Matthias; Kirsten, Holger; B. Sieber, Karsten; Qiu, Chengxiang; Gorski, Mathias; Yu, Zhi; Giri, Ayush; Sveinbjornsson, Gardar; Li, Man; Y. Chu, Audrey; Hoppmann, Anselm; J. O’Connor, Luke; Prins, Bram; Nutile, Teresa; Noce, Damia; Akiyama, Masato; Cocca, Massimiliano; Ghasemi, Sahar; J. van der Most, Peter; Horn, Katrin; Xu, Yizhe; Fuchsberger, Christian; Sedaghat, Sanaz; Afaq, Saima; Amin, Najaf; Ärnlöv, Johan; J. L. Bakker, Stephan; Bansal, Nisha; Baptista, Daniela; Bergmann, Sven; L. Biggs, Mary; Biino, Ginevra; Boerwinkle, Eric; P. Bottinger, Erwin; S. Boutin, Thibaud; Brumat, Marco; Burkhardt, Ralph; Campana, Eric; Campbell, Archie; Campbell, Harry; J. Carroll, Robert; Catamo, Eulalia; C. Chambers, John; Ciullo, Marina; Pina Concas, Maria; Coresh, Josef; Corre, Tanguy; Cusi, Daniele; Cinzia Felicita, Sala; H. de Borst, Martin; De Grandi, Alessandro; de Mutsert, Renée; P. J. de Vries, Aiko; Delgado, Graciela; Demirkan, Ayşe; Devuyst, Olivier; Dittrich, Katalin; Eckardt, Kai-Uwe; Ehret, Georg; Endlich, Karlhans; K. Evans, Michele; T. Gansevoort, Ron; Gasparini, Paolo; Giedraitis, Vilmantas; Gieger, Christian; Girotto, Giorgia; Gögele, Martin; D. Gordon, Scott; F. Gudbjartsson, Daniel; Gudnason, Vilmundur; Haller, Toomas; Hamet, Pavel; B. Harris, Tamara; Hayward, Caroline; A. Hicks, Andrew; Hofer, Edith; Holm, Hilma; Huang, Wei; Hutri-Kähönen, Nina; Hwang, Shih-Jen; Arfan Ikram, M.; M. Lewis, Raychel; Ingelsson, Erik; Jakobsdottir, Johanna; Jonsdottir, Ingileif; Jonsson, Helgi; K. Joshi, Peter; Shilpa Josyula, Navya; Jung, Bettina; Kähönen, Mika; Kamatani, Yoichiro; Kanai, Masahiro; M. Kerr, Shona; Kiess, Wieland; E. Kleber, Marcus; Koenig, Wolfgang; S. Kooner, Jaspal; Körner, Antje; Kovacs, Peter; K. Krämer, Bernhard; Kronenberg, Florian; Kubo, Michiaki; Kühnel, Brigitte; La Bianca, Martina; A. Lange, Leslie; Lehne, Benjamin; Lehtimäki, Terho; Liu, Jun; Loeffler, Markus; J. F. Loos, Ruth; Lyytikäinen, Leo-Pekka; Magi, Reedik; Mahajan, Anubha; G. Martin, Nicholas; März, Winfried; Mascalzoni, Deborah; Matsuda, Koichi; Meisinger, Christa; Meitinger, Thomas; Metspalu, Andres; Milaneschi, Yuri; J. O’Donnell, Christopher; D. Wilson, Otis; Michael Gaziano, J.; P. Mishra, Pashupati; L. Mohlke, Karen; Mononen, Nina; W. Montgomery, Grant; O. Mook-Kanamori, Dennis; Müller-Nurasyid, Martina; N. Nadkarni, Girish; A. Nalls, Mike; Nauck, Matthias; Nikus, Kjell; Ning, Boting; M. Nolte, Ilja; Noordam, Raymond; R. O’Connell, Jeffrey; Olafsson, Isleifur; Padmanabhan, Sandosh; W. J. H. Penninx, Brenda; Perls, Thomas; Peters, Annette; Pirastu, Mario; Pirastu, Nicola; Pistis, Giorgio; Polasek, Ozren; Ponte, Belen; J. Porteous, David; Poulain, Tanja; H. Preuss, Michael; J. Rabelink, Ton; M. Raffield, Laura; T. Raitakari, Olli; Rettig, Rainer; Rheinberger, Myriam; M. Rice, Kenneth; Rizzi, Federica; Robino, Antonietta; Rudan, Igor; Krajcoviechova, Alena; Cifkova, Renata; Rueedi, Rico; Ruggiero, Daniela; A. Ryan, Kathleen; Saba, Yasaman; Salvi, Erika; Schmidt, Helena; Schmidt, Reinhold; M. Shaffer, Christian; V. Smith, Albert; H. Smith, Blair; N. Spracklen, Cassandra; Strauch, Konstantin; Stumvoll, Michael; Sulem, Patrick; M. Tajuddin, Salman; Teren, Andrej; Thiery, Joachim; H. L. Thio, Chris; Thorsteinsdottir, Unnur; Toniolo, Daniela; Tönjes, Anke; Tremblay, Johanne; G. Uitterlinden, André; Vaccargiu, Simona; van der Harst, Pim; M. van Duijn, Cornelia; Verweij, Niek; Völker, Uwe; Vollenweider, Peter; Waeber, Gerard; Waldenberger, Melanie

doi:10.1038/s41588-019-0504-x

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Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

Shared by NobleBlocks on Oct 1, 2019 • 12:00 AM UTC

Authors:

German Chronic Kidney Disease Study

Adrienne Tin

Lifelines Cohort Study

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