Gut microbiota from colorectal cancer patients enhances the progression of intestinal adenoma in Apcmin/+ mice

Lü, Li; Li, Xiaofei; Zhong, Weilong; Yang, Min; Xu, Mengque; Sun, Yue; Ma, Jiaheng; Liu, Tianyu; Song, Xueli; Dong, Wenxiao; Liu, Xiang; Chen, Yange; Liu, Yi; Abla, Zaripa; Liu, Wentian; Wang, Bangmao; Jiang, Kui; Cao, Hailong

doi:10.1016/j.ebiom.2019.09.021

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Gut microbiota from colorectal cancer patients enhances the progression of intestinal adenoma in Apcmin/+ mice

Published in EBioMedicine • Oct 1, 2019

Authors:

Li Lü

Xiaofei Li

Weilong Zhong

Abstract

BACKGROUND: Accumulating evidence points to a close relationship between gut dysbiosis and colorectal cancer (CRC). As >90% of CRC develop from adenoma, we aimed to investigate the crucial role of imbalanced gut microbiota on the progression of intestinal adenoma. METHODS: mice gavage with phosphate...

Subject

Colorectal cancer

Adenoma

Medicine

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