METTL3-mediated m <sup>6</sup> A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance

Wang, Qiang; Chen, Chen; Ding, Qingqing; Zhao, Yan; Wang, Zhangding; Chen, Junjie; Jiang, Zerun; Zhang, Yan; Xu, Guifang; Zhang, Jingjing; Zhou, Jianwei; Sun, Beicheng; Zou, Xiaoping; Wang, Shouyu

doi:10.1136/gutjnl-2019-319639

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METTL3-mediated m 6 A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance

Published in Gut • Oct 3, 2019

Authors:

Qiang Wang

Chen Chen

Qingqing Ding

Abstract

Objective N 6 -methyladenosine (m 6 A) RNA methylation and its associated methyltransferase METTL3 are involved in tumour initiation and progression via the regulation of RNA function. This study explored the biological function and clinical significance of METTL3 in gastric cancer (GC). Design The ...

Subject

Angiogenesis

Cancer research

Metastasis

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