Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort

Hutchison, Iain; Ridout, Fran; Cheung, Sharon; Shah, Neil; Hardee, P.; Surwald, Christian; Thiruchelvam, J.; Cheng, Leo; Mellor, Tim; A. Brennan, Peter; J. Baldwin, Andrew; Shaw, Richard; Halfpenny, W.; Danford, M.; Whitley, Simon; A. Smith, Graham; Bailey, M; Woodwards, Bob; Patel, Manu; McManners, J.; Chan, Chi-Hwa; Burns, Andrew; Praveen, Prav; Camilleri, Andrew; Avery, Chris; Putnam, Graham; G. Jones, Keith; Webster, Keith; P. Smith, William; Edge, C.J.; McVicar, Iain; Grew, Nick; Hislop, Stuart; Kalavrezos, Nicholas; Martin, I.C.; Hackshaw, Allan

doi:10.1038/s41416-019-0587-2

Public

Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort

Published in British Journal of Cancer • Oct 14, 2019

Authors:

Iain Hutchison

Fran Ridout

Sharon Cheung

Abstract

BACKGROUND: Guidelines remain unclear over whether patients with early stage oral cancer without overt neck disease benefit from upfront elective neck dissection (END), particularly those with the smallest tumours. METHODS: We conducted a randomised trial of patients with stage T1/T2 N0 disease, who...

Subject

Medicine

Neck dissection

Meta-analysis

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