Treatment of metabolic acidosis with sodium bicarbonate delays progression of chronic kidney disease: the UBI Study

UBI Study Group, The; Di Iorio, Biagio; Bellasi, Antonio; L. Raphael, Kalani; Santoro, Domenico; Aucella, Filippo; Garofano, Luciano; Ceccarelli, Michele; Di Lullo, Luca; Capolongo, Giovanna; Di Iorio, Mattia; Guastaferro, Pasquale; Capasso, Giovambattista

doi:10.1007/s40620-019-00656-5

Public

Treatment of metabolic acidosis with sodium bicarbonate delays progression of chronic kidney disease: the UBI Study

Published in Journal of Nephrology • Oct 9, 2019

Authors:

The UBI Study Group

Biagio Di Iorio

Antonio Bellasi

Abstract

BACKGROUND: Metabolic acidosis is associated with accelerated progression of chronic kidney disease (CKD). Whether treatment of metabolic acidosis with sodium bicarbonate improves kidney and patient survival in CKD is unclear. METHODS: We conducted a randomized (ratio 1:1). open-label, controlled tr...

Subject

Medicine

Metabolic acidosis

Sodium bicarbonate

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