Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn

J. Spechler, Stuart; G. Hunter, John; Jones, Karen; Lee, Robert; R. Smith, Brian; Mashimo, Hiroshi; M. Sanchez, Vivian; B. Dunbar, Kerry; Pham, Thai; K. Murthy, Uma; Kim, Taewan; S. Jackson, Christian; Wallen, Jason; C. von Rosenvinge, Erik; P. Pearl, Jonathan; Laine, Loren; W. Kim, Anthony; M. Kaz, Andrew; P. Tatum, Roger; F. Gellad, Ziad; Lagoo‐Deenadayalan, Sandhya; H. Rubenstein, Joel; A. Ghaferi, Amir; Lo, Wai–Kit; Fernando, Ronald; S. Chan, Bobby; Paski, Shirley; Provenzale, Dawn; O. Castell, Donald; Lieberman, David; F. Souza, Rhonda; D. Chey, William; Warren, Stuart; Davis‐Karim, Anne; D. Melton, Shelby; M. Genta, Robert; Serpi, Tracey; Biswas, Kousick; D. Huang, Grant

doi:10.1056/nejmoa1811424

Public

Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn

Published in New England Journal of Medicine • Oct 16, 2019

Authors:

Stuart J. Spechler

John G. Hunter

Karen Jones

Abstract

BACKGROUND: Heartburn that persists despite proton-pump inhibitor (PPI) treatment is a frequent clinical problem with multiple potential causes. Treatments for PPI-refractory heartburn are of unproven efficacy and focus on controlling gastroesophageal reflux with reflux-reducing medication (e.g., ba...

Subject

Medicine

Randomized controlled trial

Refractory (planetary science)

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